Figure  6: Effect of g_Na on meandering patterns. (C) Tip-trajectory evolution during 500 ms (i-iii) and 110 ms (I-III). for different g_Na values: (C.i,I) g_Na = 2.0 mS, (C.ii,II) g_Na = 2.5 mS - standard value for guinea-pig ventricular model, (C.iii,III) g_Na= 3.0 mS. The evolution of the spiral tip-trajectory is shown in (A) forg_Na = 2.0 mS and (B) for g_Na = 3.0 mS. In the enlarged panel of (A) and (B) the total duration of tip-trajectory evolution is 1100 ms corresponding to the interval 1400-2500 ms of simulation in which a spiral was initiated using the phase distribution method. The corresponding plots (a-k) show thesame simulation in successive 100ms intervals. The region shown here is 4.0×4.0 mm² . The horizontal solid bars are 1 mm long.